吡唑及其衍生物具有抗微生物、抗肿瘤、抗病毒、抗抑郁等药理活性,在吡唑上引入其他环状基团后可生成大量先导化合物,其中,环丙基的引入在药物分子发挥着多种作用:降低血浆清除率、降低脱靶作用、增加血脑屏障渗透率、增强对受体的亲和力、限制多肽的水解作用、改善药物的解离度。

844872-73-7 Ethyl 1-cyclopropyl-3-methyl-1H-pyrazole-5-carboxylate
BD760517844872-73-797%
¥2565.0100mg
1240565-06-3 1-Cyclopropyl-1H-pyrazol-3-amine
BD4463531240565-06-398%
¥1400.01g
1823349-88-7 1-Cyclopropyl-1H-pyrazole-3-carbaldehyde
BD014401991823349-88-798%
¥887.0100mg
1622840-18-9 3-Bromo-1-cyclopropyl-1H-pyrazole
BD009229741622840-18-997%
¥2400.01g
1393532-43-8 1-Cyclopropyl-1H-pyrazole-5-carboxylic acid
BD7605821393532-43-897%
¥2500.01g
1622883-44-6 1-Cyclopropyl-1H-pyrazole-4-carboxylic acid
BD7581221622883-44-697%
¥344.0100mg
1338718-38-9 5-Chloro-1-cyclopropyl-4-nitro-1H-pyrazole
BD3290641338718-38-998%
¥2458.01g
1346462-59-6 1-Cyclopropyl-3-methyl-1h-pyrazol-5-amine
BD011653501346462-59-695%
¥1991.01g
1517978-30-1 5-Bromo-1-cyclopropyl-1H-pyrazole
BD008002711517978-30-197%
¥2880.01g
1403333-94-7 1-Cyclopropyl-1H-pyrazole-3-carboxylic acid
BD7605811403333-94-798%
¥2880.01g
1440965-10-5 3-Chloro-6-(1-cyclopropyl-1H-pyrazol-4-yl)pyridazine
BD7484231440965-10-598%
¥850.01g
2380267-91-2 tert-Butyl (1-cyclopropyl-1H-pyrazol-3-yl)carbamate
BD023685212380267-91-298%
¥865.01g
1240570-44-8 1-Cyclopropyl-5-methyl-1H-pyrazol-3-amine
BD011356131240570-44-897%
¥6150.01g
1898283-96-9 2-Chloro-4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridine
BD008649431898283-96-995%
¥26767.01g
1783435-57-3 3-Chloro-1-cyclopropyl-pyrazole
BD008268351783435-57-398%
¥8030.01g
2089319-10-6 1H-Pyrazol-4-amine, 1-cyclopropyl-, hydrochloride (1:2)
BD007041832089319-10-695+%
¥4225.01g
1995071-82-3 1-Cyclopropyl-1h-pyrazole-3-sulfonyl chloride
BD008552161995071-82-395%
¥6887.0250mg
N/A 1-Cyclopropyl-4-methyl-1H-pyrazole
BD00761902N/A95%
¥6500.01g
1240579-10-5 1-Cyclopropyl-3-nitro-1H-pyrazole
BD008490781240579-10-598%
¥4956.01g
N/A 1-Cyclopropyl-4-fluoro-1H-pyrazole
BD00760225N/A95%
¥6500.01g
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