克罗拉滨能抑制核苷酸还原酶,IC50为65 nM,还能抑制DNA聚合酶活性,是嘌呤核苷抗代谢产物。在至少两种其他类型的治疗已经失败后,这是FDA批准的治疗儿童复发或难治性急性淋巴细胞白血病(ALL)的药物。

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34371-14-7 (4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
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5451-40-1 2,6-Dichloropurine
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1839-18-5 2-Chloro-7H-purin-6-amine
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¥561.005g
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