艾伏磷酰胺是一种缺氧 (hypoxia) 激活前药,缺氧 (N2) 和常氧 (21% O2) 环境下,IC50 分别为 10 μM 和 1000 μM,是一种在临床上开发用于癌症治疗的低氧激活的前体药物。

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