吉格列汀(rINN)以前被鉴定为LC15-0444,是新型二肽基肽酶-4(DPP-4)抑制剂类药物的口服抗高血糖剂(抗糖尿病药物)。众所周知,DPP-4抑制剂的降糖作用主要由GLP-1和胃抑制多肽(GIP)内分泌激素介导,而胃抑制多肽(GIP)内分泌激素被DPP-4失活。

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