含肽段连接子是一类包含特定序列短肽的连接子,这类酶可裂解连接子已广泛应用于抗体偶联药物(ADC)中。ADC的作用机制是借助抗体的靶向性被精准的输送到靶细胞,接着由内吞途径进入细胞内,由于细胞内的溶酶体存在高浓度的蛋白水解酶,从而为含肽链连接子提供了在细胞内选择性裂解的机会,最终可以实现有效载荷的控制性释放。

按化学元素
Bx
Cx
Nx
Ox
Fx
Six
Px
Sx
Clx
Brx
Ix
按纯度: 99+% 99% 98+% 98% 97+% 97% 96+% 96% 95+% 95% 93% 90+% 90%
清空选项
2112738-13-1 4-((2S,5S)-19-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-isopropyl-4,7,17-trioxo-2-(3-ureidopropyl)-10,13-dioxa-3,6,16-triazanonadecanamido)benzyl (4-nitrophenyl) carbonate
BD008566122112738-13-198%
¥12467.001g
2055024-64-9 Azido-peg4-val-cit-pab-oh
BD008124702055024-64-998%
¥12747.001g
2055047-18-0 4-((14S,17S)-1-Azido-14-isopropyl-12,15-dioxo-17-(3-ureidopropyl)-3,6,9-trioxa-13,16-diazaoctadecan-18-amido)benzyl (4-nitrophenyl) carbonate
BD011112932055047-18-098%
¥7720.0050mg
2249935-92-8 4-((S)-2-((S)-2-(3-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)propanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl (4-nitrophenyl) carbonate
BD012020302249935-92-896%
¥15783.00100mg
2353409-45-5 BCN-PEG3-VC-PFP Ester
BD011924472353409-45-596%
¥13937.00100mg
916746-27-5 (S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanoic acid
BD01442568916746-27-598%
¥2442.00250mg
2504147-59-3 (5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoyl)-L-valyl-L-arginine
BD014390972504147-59-395%
¥5815.00100mg
2504147-53-7 Mal-amido-PEG2-Val-Cit-PAB-OH
BD014237902504147-53-795%
¥8953.00100mg
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