塔兹门头司是一种有效，选择性，口服的 EZH2 抑制剂，Ki 和 IC50 分别为2.5和11 nM。
3-(Aminomethyl)-4,6-dimethylpyridin-2(1H)-one
5-Bromo-2-methyl-3-nitrobenzoic acid
Methyl 5-bromo-2-methyl-3-((tetrahydro-2H-pyran-4-yl)amino)benzoate
Dihydro-2H-pyran-4(3H)-one
4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine
2-Methyl-3-nitrobenzoic acid
5-Bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzoic acid
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide
Methyl 5-bromo-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzoate
