布罗福韦酯(CMX001) 是一种具有口服活性的Cidofovir (CDV) 亲脂形式,对某些疱疹病毒,腺病毒和正痘病毒,比CDV具有更强的体内外活性。 是一种用于治疗巨细胞病毒、腺病毒、天花和埃博拉病毒感染的实验性抗病毒药物。布罗福韦酯是西多福韦的前药。与脂质结合,该化合物被设计为在细胞内释放西多福韦,允许更高的细胞内浓度和更低的血浆浓度西多福韦,有效提高其对dsDNA病毒的活性以及口服生物利用度。

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