依鲁替尼是选择性，不可逆的 Btk 抑制剂，IC50 值为 0.5 nM，是一种小分子药物，与B细胞中重要的蛋白Bruton酪氨酸激酶(BTK)永久结合；该药物用于治疗B细胞癌，如外套细胞淋巴瘤、慢性淋巴细胞白血病和Waldenstrm的大球蛋白血症。
1H-Pyrazolo[3,4-d]pyrimidin-4-amine
(S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate
(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
3-Amino-5-(4-phenoxyphenyl)pyrazole-4-carbonitrile
(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
(4-Phenoxyphenyl)boronic acid
3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
2-(Methoxy(4-phenoxyphenyl)methylene)malononitrile
4-Phenoxybenzoic acid
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
4-Phenoxybenzoyl chloride
2-(Hydroxy(4-phenoxyphenyl)methylene)malononitrile
