阿伐那非是高活性PDE-5抑制剂，IC50为5.2 nM，对PDE1，PDE6和PDE11活性较低，勃起功能障碍的PDE5抑制剂。
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Diethyl 2-(ethoxymethylene)malonate
2,4-Dichloro-5-pyrimidinecarbonyl chloride
Pyrimidin-2-ylmethanamine
4-(Bromomethyl)-2-chloro-1-methoxybenzene
4-Chloro-2-(methylthio)pyrimidine-5-carbonyl chloride
(S)-Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Ethyl 2-(methylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxylate
3-Chloro-4-methoxybenzylamine Hydrochloride
Ethyl 4-amino-2-hydroxypyrimidine-5-carboxylate
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
L-Prolinol
4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid
3-Chloro-4-methoxybenzylamine
6-Aminopyrimidin-2(1H)-one
Pyrimidin-2-ylmethanamine hydrochloride
Methyl carbamimidothioate
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
2-Chloro-4-(chloromethyl)-1-methoxybenzene
Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate
4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
