硼替佐米是有效的 20S 蛋白酶体 (20S proteasome) 抑制剂，Ki 为 0.6 nM，是一种抗肿瘤药物，是人类应用的第一种治疗性蛋白酶体抑制剂。蛋白酶体是分解蛋白质的细胞复合物。在一些癌症中，通常杀死癌细胞的蛋白质被分解得太快。硼替佐米阻断了这一过程，并让这些蛋白质杀死癌细胞。在美国和欧洲被批准用于治疗复发性多发性骨髓瘤和套细胞淋巴瘤。
(R)-3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride
5,5,5',5'-Tetramethyl-2,2'-bi(1,3,2-dioxaborinane)
Isobutylboronic acid
2-Isobutyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
(1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol
((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
(R)-2-Methyl-2-propanesulfinamide
Pyrazine-2-carboxylic acid
4,4,4',4',5,5,5',5'-Octamethyl-2,2'-bi(1,3,2-dioxaborolane)
(S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid
H-Phe-OMe.HCl
(S)-Methyl 2-amino-3-phenylpropanoate
Boc-Phe-OH
3-Methyl-1-(tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine hydrochloride
