克唑替尼是一种有效的 c-Met 和 ALK 的抑制剂，IC50 值分别为 11 nM 和 24 nM。它是作为ALK(间变性淋巴瘤激酶)和ROS1(c-ros癌基因1)抑制剂的抗癌药物。
4-Iodopyrazole
2-Amino-5-bromo-3-pyridinol
1H-Pyrazole
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
tert-Butyl 4-hydroxypiperidine-1-carboxylate
1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine
tert-Butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate
tert-Butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate
4-(1H-Pyrazol-1-yl)piperidine
4-(4-Iodo-1H-pyrazol-1-yl)piperidine
4,4,4',4',5,5,5',5'-Octamethyl-2,2'-bi(1,3,2-dioxaborolane)
4-Chloropyridine hydrochloride
2',6'-Dichloro-3'-fluoroacetophenone
2-Nitropyridin-3-ol
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
(R)-5-Bromo-N,N-bis-(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
tert-Butyl (5-bromo-3-hydroxypyridin-2-yl)carbamate
(R)-tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
1-(2,6-Dichloro-3-fluorophenyl)ethanol
